It is not uncommon for people to combine LSD with another psychedelic. However, if a person is on a pharmaceutical medication—specifically an SSRI—certain considerations should be taken into account.1
Taking LSD in Combination with Other Substances
Things to Know
- LSD became popular in the 1950s for psychedelic-assisted psychotherapy
- In the counterculture movement of the 1960s, LSD was widely used to enhance creativity and for spiritual insights
- Albert Hofmann, the chemist who originally synthesized LSD, called it medicine for the soul
- LSD can be used for personal enhancement, a greater connection with nature, creativity, and spirituality
Candy Flipping: LSD and MDMA
Research2 suggests that a combination of MDMA and LSD in subjects produces mostly positive results. However, much caution is needed when engaging in this practice. Known as “candy flipping” in popular culture, this combination may be more intense than each of the substances alone. Generally speaking, candy flipping is safe, so long as the dosages of each remain moderate.3
LSD and Alcohol
For some people, alcohol4 in combination with LSD may soften the effects of the LSD. The LSD may also distort one’s perception of the alcohol’s effects, which could lead to unsafe behaviors.
LSD and SSRIs
Generally speaking, if one is on SSRIs, the medication may blunt the effects of the LSD. More information can be found here.
Other LSD Combinations
Other substance combinations5 that include LSD are Jedi Flipping (LSD, MDMA, and psilocybin), Banana Flipping (LSD and 2CB), Ali Flipping (LSD, 2CB, and MDMA), Cosmo Flipping (LSD and DMT), Gasid (LSD and nitrous), and Outer Limits (LSD and Cocaine).