Discover the plants, fungi and compounds that create non-ordinary forms of awareness and expanded states of consciousness.

To learn best practices developed by harm reduction experts for the novice and intrepid psychonaut alike, start here.

Psychedelic use can be profound sometimes, helpful other times, risky occasionally, and in rare cases dangerous. Know your psychedelics.


Ketamine is a legal dissociative anesthetic that is used off-label in clinics for conditions including depression and trauma.


LSD is a potent synthetic psychedelic substance which has had a profound impact on culture, science and spirituality.


MDAM (also "Ecstasy" or "Molly") is a potent empathogen with effects that include altered sensations, increased energy, empathy, and pleasure.

Psilocybin Mushrooms

Psilocybin mushrooms, sometimes called magic mushrooms or "shrooms" for short, are a class of psychedelic fungi that grow naturally around the world.

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The Latest in Substances

Ketamine for Pain

July 6th, 2023

UPDATED: August 2nd, 2023

Ketamine research also suggests it has pain relieving qualities . A 2004 study analyzed…

How to Take Ketamine

July 6th, 2023

UPDATED: August 2nd, 2023

At moderate to higher subanesthetic doses, ketamine typically produces dissociative or psychedelic effects, ranging…

Ketamine for Conditions

July 6th, 2023

UPDATED: August 2nd, 2023

Ketamine is being used to treat an array of mental health conditions and substance…

Ketamine-Assisted Therapy

July 20th, 2023

UPDATED: August 2nd, 2023

Long used as an anesthetic, the use of ketamine as a possible therapeutic agent…

Ketamine in Combination with Other Substances

July 21st, 2023

UPDATED: July 31st, 2023

Ketamine is often combined with other drugs to create an amplified dissociative or psychedelic…

Best Practices

June 20th, 2023

UPDATED: July 21st, 2023

There are myriad ways to experience psychedelics, from clinical therapy to ceremony to recreationally…

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